Dr. Castroflorio obtained his DDS Degree from the University of Torino, Italy, in 1998; In 2001 he was certified as a Specialist in Orthodontics summa cum laude from the same University. In 2007 he obtained his PhD in Human Morphology from the University of Milan, Italy. In 2009 he completed a postgraduate course in Orofacial Pain at the University of New Jersey, USA.

Since 2014 he is an aggregate Professor of the Chair of Orthodontics and of the Specialization School of Orthodontics of the Dental School of the University of Torino, Torino, and since 2019 he is the vice-director of the post-graduate School in Orthodontics of the University of Torino, Italy. He is involved in research projects focused on aligner, bracket-archwire interactions, and orthodontic tooth movement biology.
He is author or co-author of more than 100 publications on peer-review journals, national dental journals and of chapters of books.

He serves as reviewer for the most important dental journals in the field of Orthodontics and Oral Physiology. He is member of the Editorial Board of the Journal of Aligner Orthodontics.

He is a founding member and board member of the European Aligner Society

His private practice is located in Torino, Italy.